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Tag Archive 'gastroenterology'

AFTB Lecture Notes - Acute Liver Failure

Posted in AFTB lecture, Hepatology, education, elearning, emergency medicine, evidence based medicine, gastroenterology, lecture on Oct 4th, 2008

DEFINITION

Hyperacute liver failure

Presents within 7 days of onset. 36% survival with medical management alone (single most common cause in UK and USA is paracetamol poisoning).

Acute liver failure

Encephalopathy, coagulopathy and jaundice presenting within 8-28 days in patient with previously normal liver. More likely (with hyperacute group) to get cerebral oedema (80%).

Subacute liver failure

Presents from 29-72 days, [...]

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AFTB Lecture Notes - Oesophagogastric Varices

Posted in AFTB lecture, Hepatology, education, elearning, emergency medicine, evidence based medicine, gastroenterology, lecture on Oct 4th, 2008

EPIDEMIOLOGY

5-12% upper G1 bleeds.
50% cirrhosis patients have varices, up to 85% in Child-Pugh C patients.
25-35% of patients with chronic liver disease will have a variceal bleed, which accounts for 80-90% of bleeding episodes in those patients.
Mortality of a first bleed 30%, with rebleeding in 30-60% after banding / sclerotherapy, and 32-80% 1-year mortality.

MANAGEMENT

Endoscopic:

Banding ligation.  Lower [...]

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